Persia is a city in Harrison County, Iowa, United States. The population was 297 in the 2020 census, a decline from 363 in the 2000 census. …Persia is a city in Harrison County, Iowa, United States. The population was 297 in the 2020 census, a decline from 363 in the 2000 census. According to the United States Census Bureau, the city has a total area of 0.47 square miles, all of it land.