The Buffalo Bills have not topped the AFC regular season standings in more than 30 years, but that could change

The Buffalo Bills still have plenty of time to make roster decisions. Another preseason contest against the Tampa Bay Buccaneers awaits the team next weekend. After that, all 32 teams in the NFL will have to trim their rosters to 53 players from the 90 currently on their depth charts. Roster cut-down day is slated for Tuesday, Aug. 26.

Week 2 of the NFL preseason is almost in the books, and we're breaking down our expert predictions for Bills vs. Bears.

This article was originally published on www.si.com/nfl/bills as Buffalo Bills 53-man roster prediction after NFL preseason Week 2. The Buffalo Bills lost in ugly fashion this past weekend to the Chicago Bears, dropping them to 0-2 in the 2025 NFL preseason.

Chris Vasile breaks down the NFL preseason Week 3 slate and offers his best NFL predictions and moneyline picks.

While it was only preseason, Saturday can’t come soon enough for Bills fans looking to cleanse their pallet after watching the Bills get shutout by the Bears, 38-0 Sunday night. So now it’s on to Tampa Bay,

While trimming their roster to 53 players, the Buffalo Bills could look to trade these 3 players who are on the roster bubble.

Preseason results rarely matter in the long run, but when the scoreboard shows 38-0 as it did Sunday for the Buffalo Bills in a loss to the Chicago Bears, it's hard to simply shrug it off. Coach Sean McDermott didn't mince words after the blowout,