49ers host Matthew Stafford and the Rams
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San Francisco 49ers head coach Kyle Shanahan announced the team's starting quarterback for Week 10's matchup against the Rams.
Preview the San Francisco 49ers' NFL week 10 matchup with the Rams, including betting odds, tips, trends, and game information.
San Francisco tight end George Kittle explained why the 49ers' games against the Los Angeles Rams stand out to him ahead of their Week 10 matchup.
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How will the depleted 49ers defense attack the Rams?
The 49ers have really struggled to get pressure on teams this season, especially after Nick Bosa’s season-ending injury. That prompted Saleh to go with a more aggressive approach two weeks ago against the Houston Texans, which didn’t work out as C.J. Stroud had his best game of the season.
Los Angeles Rams kicker Harrison Mevis is set to make his NFL debut during Sunday's Week 10 matchup at the San Francisco 49ers, head coach Sean McVay told reporters Friday.
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Rams at 49ers prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats
Despite a wave of injuries to key position groups, San Francisco has persevered and is right in the thick of an ultra-competitive NFC West. Somewhat ironically, running back Christian McCaffrey has remained healthy throughout the season. The All-Pro leads the NFL in yards from scrimmage.
For the 49ers, Ricky Pearsall remained a non-participant, missing practice once again. Brock Purdy was limited for the second straight day and is uncertain to play against the Rams, while Dee Winters was downgraded from limited to DNP.