Recent data have shown that many pathogens are dependent on clathrin and actin for their entry into host cells. The study of pathogen entry has revealed the flexibility of clathrin to accommodate both ...

Newly published research by Indiana University structural biologist Joel Ybe and colleagues identifies a "topology switch" in the protein clathrin, the function of which may shed light on molecular ...

Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and conveyed ...

In clathrin-mediated endocytosis, the cell membrane invaginates to take up metabolites, hormones, and proteins from the cell surface into intracellular vesicles. Cells employ several pathways for ...

Clathrin proteins involved in endocytosis form a lattice that can dramatically change its shape Combination of fluorescence microscopy and 3D electron microscopy allows quantitative data to be ...

In an upcoming G&D paper, Dr. Yoichi Taya (National Cancer Center Research Institute, Japan) and colleagues report on a novel nuclear role for the clathrin heavy chain protein as a p53-dependent ...