DNA, the blueprint of life, is best known for its fundamental role as genetic material—storing and transmitting biological information through the precise sequence of its bases. For decades, this ...
The DNA double helix is composed of two DNA molecules whose sequences are complementary to each other. The stability of the duplex can be fine-tuned in the lab by controlling the amount and location ...
DNA's iconic double helix does more than "just" store genetic information. Under certain conditions, it can temporarily fold ...
From synthetic biology and gene therapy to data storage and biofuel production, the demand for synthetic DNA is rising. (1) Chemicals remove the 5’-hydroxyl protecting group. The nucleosides are rich ...
Nowadays, there's lots of buzz about spectacular new medical treatments such as personalised cancer therapy with modified immune cells or antibodies. Such treatments, however, are very complex and ...
A strand of RNA just 45 nucleotides long has been discovered to perform two key reactions required for self-replication. The molecule, which is a kind of RNA enzyme, offers a tantalising clue towards ...
The discovery of catalytic RNA transformed our understanding of life's beginnings. Clare Sansom explores how the RNA world ...
Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal metabolic processes or external stressors such as radiation or chemical ...
A screenshot of a Google Doodle, which is drawn in light and dark purple and shows a cartoonish DNA double helix, the structure of guanine and a phosphate group, and small cartoons of a chromosome and ...