Experimentation is a vital part of the scientific method. Most problems in science require observation of the system at work and experimentation to elucidate information about how the system works. In ...

This example FACTEXG1 introduces the basic syntax used with the FACTEX procedure. An experimenter is interested in studying the effects of three factors - cutting speed (SPEED), feed rate (FEED), and ...

The author prepared and analyzed a detailed design of experiments for the manufacture of a simple tablet formulation. The aim was to test whether tablet hardness and weight could be controlled during ...

Formulation development can involve several complex technical challenges, but an approach incorporating design of experiments can help address these difficulties. All pharmaceutical drug products are ...

The classical design (factorial design, response surface design, etc.) may fail to meet our requirements due to an irregular design space, involving categorical variables, a nonstandard model, or ...

Ethics committees and funding agencies often receive protocols that involve either too many or too few animals to answer the specific research question being investigated. It is evident that a greater ...

What is a foldover design? A design created by adding an identical but complementary fraction to an original fraction of a factorial design in statistical experiments. The new design has twice the ...

The previous example illustrates a complete factorial experiment involving eight runs and three factors: cutting speed (SPEED), feed rate (FEED), and tool angle (ANGLE). Now, suppose two machines (A ...