Sustained Hedgehog (HH) signaling is implicated in basal cell carcinoma of the skin and other types of cancer. Here we show that GLI1 and GLI2, the main transcriptional activators of the HH pathway, ...
The Sonic hedgehog (Shh) signal-transduction pathway is involved in the patterning, growth and survival of many cells and tissues, and its deregulation has been implicated in several cancers. The ...
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