Penicillins are a group of antibacterial drugs that attack a wide range of bacteria. They were the first drugs of this type that doctors used. These drugs have saved millions of lives. Penicillium ...

The introduction of methicillin in September, I960, 77, 78 provided a drug with a unique property not found in earlier penicillins — namely, resistance to hydrolysis by penicillinase. Within the ...

It is considered potentially harmful to administer imipenem–cilastatin to patients with IgE-mediated hypersensitivity to penicillins 1 because of a 47.4 percent rate of cross-reactivity (9 of 19 ...

Antibiotics are medications that treat bacterial infections. They achieve this by killing bacteria or slowing their growth. Some common types of antibiotics include penicillin and macrolides. Medical ...

Karen Hopkin is a freelance science writer in Somerville, Mass. She holds a doctorate in biochemistry and is a contributor to Scientific American's 60-Second Science podcasts. If you enjoyed this ...

The penicillin family represents one of the most valuable groups of antibiotics in practically every area of modern healthcare. They are bactericidal, well distributed, and highly effective against ...

Beta-lactam antibiotics are the most commonly prescribed group of drugs, sharing together a specific structural feature of the beta-lactam ring. Among them, penicillin is one of the earliest ...

WHILE studying the kinetics of penicillinase inactivation of various penicillins, it became evident that a penicillinase-susceptible penicillin, such as benzyl-penicillin, behaved differently from ...

Two groups of enzymes hydrolyse penicillins (I). The earlier of the two to be reported was penicillinase 1, which opens the β-lactam ring to form the corresponding penicilloic acid (II).