Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and factors affecting oocyte quality involve the ...

A team of reproductive biologists at Nanjing Agricultural University has found that spermidine, a polyamine metabolite, helps oocytes clear away damaged mitochondria in mice, thereby improving ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Communication between oocytes and granulosa cells is essential for oocyte formation, dormancy, reawakening, and maturation. Researchers have demonstrated that a protein complex called the exocyst ...

Oocyte cryopreservation is a suitable fertility preservation option for women who are not partnered, have ethical objections to cryopreserving embryos or wish to have complete reproductive autonomy.

A human female is born with all the egg cells she will ever have. The possibility for the development of new oocytes is zero. Given this constraint, it is crucial that these gametes remain healthy and ...

Researchers have succeeded in reconstructing the ovarian environment using mouse stem cells. While growing immature egg cells -- known as oocytes -- from stem cells has been possible, the process ...

Of all the available means of fertility preservation, 1 oocyte cryopreservation by means of vitrification (very rapid freezing) provides the highest yield, not only for women with benign diseases or ...

A core set of eight proteins can transform stem cells from mice into cells that look a lot like immature egg cells called oocytes. The egglike cells could not undergo meiosis to cut the total ...

IVF research suggests the oestradiol-to-oocyte ratio may help predict outcomes in PMOS patients. Find out how hormonal ...