The rivalry takes on added meaning with the Rams, who have won three in a row since losing to the Niners in Week 5, needing to win to stay atop the division.

A storied rivalry will add another significant chapter Sunday afternoon when the San Francisco 49ers stare down the Los Angeles Rams at Santa Clara, Calif. The NFC West foes intend to stand out on top of a conference crowded with contenders.

WOODLAND HILLS, Ca. The Los Angeles Rams have proceeded as expected when finalizing their roster for Sunday's contest against the San Francisco 49ers. The Rams activated both K Harrison Mevis and LS Jake McQuaide off the practice squad.

The Los Angeles Rams and San Francisco 49ers will meet on Sunday, and Sean McVay's team is calling up two players from the practice squad.

The Rams have gone undefeated since losing to the San Francisco 49ers in overtime last month, and the team is eager to prove they can beat the 49ers on the road.

The key players on offense, Mac Jones, Christian McCaffrey, and George Kittle, will need to be on their A-game. However, there is another player the 49ers must lean on against the Rams.

The San Francisco 49ers on Saturday elevated rookie DT Sebastian Valdez and D-lineman Clelin Ferrell to face the Los Angeles Rams on Sunday.