RNA molecules are real all-rounders. They transfer the genetic information from the DNA in the cell. They regulate the activity of genes. And some of them have a catalytic effect: just like enzymes, ...

Ribozymes are RNA molecules that are capable of catalyzing a chemical reaction. Ribozymes occur naturally inside cells where they play an essential role in the ribosome, joining amino acids together ...

In new research published in the journal Angewandte Chemie, scientists applied a high throughput methodology to study the ribozyme in an innovative way. While work in this area has typically used ...

A team led by Prof. Zhang Kaiming from the University of Science and Technology (USTC) solved six conformations in the second-step self-splicing of Tetrahymena ribozyme using cryogenic electron ...

The first stage of the process to develop a DU-containing catalyst involved substituting as many of the G residues as possible by either D or U, while still retaining some detectable activity.

Although ribozymes capable of performing a wide range of reactions have been evolved in the lab, only a handful of classes of these RNA-based catalysts are found in nature. Now, a new type of ribozyme ...

RNA molecules are real all-rounders. They transfer the genetic information from the DNA in the cell. They regulate the activity of genes. And some of them have a catalytic effect: just like enzymes, ...

Santa Cruz, CA — Which came first, nucleic acids or proteins? This question is molecular biology’s version of the “chicken-or-the-egg” riddle. Genes made of nucleic acids (DNA or RNA) contain the ...

In most modern cells, DNA stores the genetic blueprint, and relies on proteins to replicate, repair and build from those blueprints. At the same time, proteins require instructions from DNA to be made ...

Important progress for RNA research: A team has discovered a new ribozyme that can label RNA molecules in living cells. RNA molecules are real all-rounders. They transfer the genetic information from ...