Antidepressants treat symptoms of depression by increasing levels of brain signaling molecules (neurotransmitters) such as serotonin, as with the most widely used type of antidepressant, selective ...

Depression continues to grapple a large proportion of the population. Given the side effects associated with the long-term use of conventional antidepressants, there is a need for novel rapid acting ...

Mirtazapine, which has a different mechanism of action, had less negative cognitive impact than escitalopram. The researchers now want to investigate whether certain patient groups, such as people ...

Choosing the right antidepressant is important. There are a vast array of antidepressants and knowing where to start can be confusing. Here are five ways that I, as a psychiatrist, think about ...

Treatment-resistant depression drug Xanamem has produced statistically significant antidepressant effects in a peer-reviewed ...

Selective serotonin reuptake inhibitors (SSRIs) are a class of medications primarily used to treat depression and anxiety disorders. Feeling down or anxious occasionally can be a typical part of life, ...

This article originally appeared on Undark. In 2006, a new study on antidepressants was making headlines with its promising results: Two-thirds of participants who tried various antidepressants ...

FMP374 is a dual-acting NMDA modulator aiming to overcome challenges with older NMDA antagonists. In preclinical TRD models, ...

Finally, on the basis of mechanism of action, vortioxetine is being studied for potentially beneficial effects on cognition. Initial data on the potentially procognitive effects of vortioxetine, ...

Regarding “Your Health: What Influencers Get Wrong About Antidepressants” (Personal Journal, Nov. 12): Another side effect users should know is that clinical bone healing appears to be negatively ...

Over the last few years, there has been an increasing number of commentators claiming that antidepressants don’t work, that pharmaceutical companies lied, and that these drugs are overprescribed ...