GC ranks as the fifth most common and fourth deadliest cancer worldwide, presenting significant health challenges, particularly in China where it is most prevalent and accounts for nearly half of ...

Drugging the Master Regulator TP53 in Cancer: Mission Possible? The following represents disclosure information provided by the author of this manuscript. All relationships are considered compensated ...

Circulating tumor DNA may be an effective biomarker for stratifying patients with small cell lung cancer who would benefit from more stringent follow-ups and clinical trial participation.Patients who ...

Efficacy and safety of darolutamide in Chinese patients with metastatic hormone-sensitive prostate cancer (mHSPC): A subpopulation analysis of the phase 3 ARASENS study. This is an ASCO Meeting ...

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for therapeutics. Among them, the Y220C mutation is the ninth most frequent and it ...

“The independent research groups, led by Prof. Scott W. Lowe and Christina Curtis,respectively, have uncovered a similar definitive pathway in the progression of gastric cancer (GC) initiated with ...

Higgins is an advocate for people with Li-Fraumeni syndrome. I was born with an inherited cancer syndrome, Li-Fraumeni syndrome (LFS). A mutation on my Tp53 cancer suppressor gene makes me susceptible ...

* One sperm donor was linked to nearly 200 births across multiple countries * Several children inherited a high-risk TP53 cancer mutation * Case exposes gaps in genetic screening //and donor ...

King Charles III shared a personal message about his experience with cancer, including that treatment for his undisclosed type of cancer will be reduced in the new year, and encouraged others to get ...