The study from St. Jude Children's Research Hospital presents a new understanding of how a VGIC, crucial for the communication of neurons and muscle cells, can become unresponsive. Scientists at St.
Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 24 (June 16, 2020), pp. 13437-13446 (10 pages) Pentameric ligand-gated ion channels (pLGICs) are ...
In a surprising new finding, neuroscientists have shown that human neurons have a much lower density of ion channels than expected, compared to the neurons of other mammals. Ion channels produce ...
Electrical impedance tomography–extracellular voltage activation technique simplifies drug screening
The EIT–EVA PCB sensor setup used to evaluate the effects of drugs on hERG channels. The sensor measures changes in extracellular resistance as voltage-gated hERG channels are activated and inhibited, ...
image: From left to right, Dr. Chia-Hsueh Lee and Dr. Hongtu Zhao of the Department of Structural Biology at St. Jude Children's Research Hospital. Dr. Lee and Dr. Zhao are co-authors of a new study ...
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