Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid ...

Pfizer and Novo Nordisk are locked in a bidding war for biotech firm Metsera as the pharmaceutical giants seek to augment ...

A study from St. Jude Children's Research Hospital uncovered an alternative binding pocket within nuclear receptors, ...

Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders. These drugs were ...

Surprising findings published in PNAS have implications for understanding and treating neurological and neuropsychiatric disorders.

A poorly characterized protein, historically thought to be a chaperon or enzyme, may actually be a key player in prostate ...

Patients with obesity and asthma who used GLP-1 receptor agonists had significantly fewer exacerbations and prednisone use ...

A once-daily oral quadruple receptor agonist induced up to 13.8% weight loss at 13 weeks among adults with overweight or ...

Opioid receptors are proteins in the nervous system that interact with opioids. Opioid receptors are part of the endogenous opioid system. This is the body’s internal system for regulating pain, ...

GLP-1 receptor agonists like Ozempic and Wegovy are backed by solid scientific evidence and can support healthy weight management. But is it possible to get the same results from a supplement? GLP-1s ...