A Z-Pack (also called a Z-Pak, Zmax, or Zithromax) is literally just azithromycin, a standard antibiotic introduced in 1992, formulated in a package of six pills, which are taken over five days.

Z-pack is a prescription medication that typically requires a daily, single dose. The dosage for strep throat in adults is 500 milligrams (mg) on the first day and 250 mg daily for the following 4 ...