The Buffalo Bills have not topped the AFC regular season standings in more than 30 years, but that could change

The Buffalo Bills still have plenty of time to make roster decisions. Another preseason contest against the Tampa Bay Buccaneers awaits the team next weekend. After that, all 32 teams in the NFL will have to trim their rosters to 53 players from the 90 currently on their depth charts. Roster cut-down day is slated for Tuesday, Aug. 26.

Chicago shut out Buffalo 38-0 after New Orleans came back to tie Jacksonville 17-17 in Week 2 of the NFL preseason

That's expected to change in Year 2 of Caleb Williams. The Bears went out and hired the hottest head coaching candidate to hit the market in years, former Detroit offensive coordinator Ben Johnson. This has been the Bears' best decision in an offseason full of surprisingly good decisions,

Buffalo Bills head coach Sean McDermott wasn't pleased with his team's performance during a lopsided 38-0 preseason loss to the Chicago Bears on Sunday night.

The Buffalo Bills face the Chicago Bears in Week 2 of the NFL preseason. Find out how to watch this game for free.

While trimming their roster to 53 players, the Buffalo Bills could look to trade these 3 players who are on the roster bubble.

Week 2 of the NFL preseason is almost in the books, and we're breaking down our expert predictions for Bills vs. Bears.

The Chicago Bears resume Week 2 of the 2025 NFL preseason hosting the Buffalo Bills today. Where to watch, stream and NFL preseason TV schedule.

This article was originally published on www.si.com/nfl/bills as Buffalo Bills 53-man roster prediction after NFL preseason Week 2. The Buffalo Bills lost in ugly fashion this past weekend to the Chicago Bears, dropping them to 0-2 in the 2025 NFL preseason.

ESPN NFL analyst Mina Kimes shared her thoughts on Caleb Williams' performance in the Chicago Bears' second preseason game.