RESULTS. Of the 126 patients analyzed, 14 (11%) had SARs ().Baseline complete blood count, demographics, and treatment history were analyzed with a univariable logistic regression model ().Age, prior ...

The clinical presentations of early idiopathic Parkinson disease (IPD) substantially overlap with those of atypical parkinsonian syndromes such as multiple system atrophy (MSA) and progressive ...

Myocardial fibrosis is a major contributor to the development and progression of heart failure. Significant progress in the understanding of its pathobiology has led to the introduction and ...

PET is a powerful molecular imaging technique that can provide functional information on living objects. However, the spatial resolution of PET imaging has been limited to around 1 mm, which makes it ...

Prostate-specific membrane antigen (PSMA)–targeting radiopharmaceuticals, such as the novel [177Lu]Lu-HTK03170, present a promising therapeutic option for metastatic castration-resistant prostate ...

PSMA PET Imaging Protocols and Reporting. The recommended imaging protocols for 68 Ga-PSMA-11 and 18 F-DCFPyL are similar. In short, the administered activity, based on the prescribing information, is ...

Granzyme B. Granzyme B, a serine protease that induces apoptosis in target cells, is released by activated CD8-positive T cells and natural killer cells, in addition to some immunosuppressive cells () ...

Recent innovative strategies have dramatically redefined the therapeutic landscape for treating multiple myeloma patients. In particular, the development and application of immunotherapy and high-dose ...

225Ac-labeled ( S )-ibuprofen-diaminobutyric acid-PSMA (SibuDAB) is a novel, albumin-binding compound in prostate-specific membrane antigen (PSMA)–targeted α-therapy of prostate cancer. It showed ...

Antiamyloid therapies for Alzheimer disease recently entered clinical practice, making imaging biomarkers for Alzheimer disease even more relevant to guiding patient management. Amyloid and tau PET ...

We introduce the Fast Algorithm for Motion Correction (FALCON) software, which allows correction of both rigid and nonlinear motion artifacts in dynamic whole-body (WB) images, irrespective of the PET ...

The NETTER-1 trial significantly improved progression-free survival with [177 Lu]Lu-DOTATATE, with a hazard ratio of 0.18 (95% CI, 0.11–0.29; P < 0.0001) ().However, 5 y after the last patient ...