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A strong CRNA interview answer would be: “Preload is the amount of stretch or filling of the ventricles before contraction. Afterload is the resistance the left ventricle has to overcome to eject the blood. So preload is essentially what fills the pump, and after load is what the pump has to push against. ✅ Prepoad = How full the heart is before it squeezes. It’s mainly influenced by how much blood is returning to the heart. More venous return usually means more ventricular filling and more stre
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